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Ukoliko je doneta odluka o propisivanju diazepama istovremeno sa opioidima, treba primenjivati najmanju efektivnu dozu a trajanje terapije treba ograničiti na što kraće vreme (videti i opšte preporuke doziranja u odeljku four.two).The FDA restricts utilization of tramadol in children on account of serious risk of slowed or tough respiratory and

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